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Hyaluronic acid is widely used in clinic


Hyaluronic acid (HA), known by another name "hyaluronic acid", is used in the field of skin care and medical beauty. Yang Rongya, director of the Skin Damage Repair Institute of the Seventh Medical Center of the People's Liberation Army General Hospital and president-elect of the Chinese Medical Association Medical Cosmetics Branch, said that hyaluronic acid is a natural substance existing in the human body itself, which plays important physiological functions such as water retention, lubrication and repair promotion in the body. However, with the growth of age and the aging of the body, the loss begins to accelerate after the age of 20. Hyaluronic acid is also a substance found in nature with good moisturizing properties, and is known as an ideal natural moisturizing factor, so it is widely used in the skin field.

Because it is safe and plastic, it has been gradually used in micro-plastic surgery and is known to more people. Li Xiaoning, director of the dermatology department of United Regal First Hospital, introduced that some people want to improve the contour, including the forehead, the back of the nose, the chin and other parts, which can be achieved by hyaluronic acid (hyaluronic acid) products; Some people just want to improve the sagging state of aging, such as lacrimal groove depression, apple muscle sag, decree lines, etc., will also choose hyaluronic acid to correct accordingly.

In fact, hyaluronic acid for "beauty" is only a "corner" of the application, and it is widely used in orthopedics, ophthalmology, dermatology, digestive endoscopy, health nutrition, and even gastrointestinal department.

"Hyaluronic acid was first used in ophthalmology." Xie Like, vice president of the Eye Hospital of China Academy of Chinese Medical Sciences, said that in clinical ophthalmic surgery such as cataract surgery and vitreoretinal surgery, sodium hyaluronate is needed to maintain the depth of the anterior chamber as a viscoelastic agent, stop bleeding, separate proliferating membranes, and plug macular holes to prevent stains from entering the retina. In addition, sodium hyaluronate is widely used in eye drops as artificial tears to treat dry eyes, or other eye drop accessories. At present, sodium hyaluronate has become an important medical material in ophthalmology.

Hyaluronic acid is also widely used in orthopedics and sports medicine. According to Hu Yuelin, chief physician of the Institute of Sports Medicine at Peking University Third Hospital, the components of normal joint fluid contain hyaluronic acid. With the increase of age, the quantity and quality of joint fluid decrease, and the wear and tear of joints increase. At this time, it is necessary to inject exogenous hyaluronic acid into the joints to ensure the content of hyaluronic acid in the joints, so that the joint functions can be normal. The injection is mainly aimed at two conditions: one is the joint function limitation caused by articular cartilage wear in young people, such as athletes; The second is mild and moderate osteoarthritis, and the use of hyaluronic acid can reduce the use of non-steroidal anti-inflammatory drugs, especially for the elderly, patients with a history of gastrointestinal ulcer and bleeding and cardiovascular and cerebrovascular diseases.

Hyaluronic acid is also used in the field of digestive endoscopy. According to Hao Jianyu, Director of the Department of Gastroenterology, Beijing Chaoyang Hospital, endoscopic submucosal dissection (ESD) is the preferred treatment for early gastric cancer. During this operation, multi-point submucosal injection is needed to lift the lesion and separate it from the muscle layer, which is conducive to complete resection of the lesion during the process and reduce the occurrence of complications such as perforation and bleeding. Normal saline is safe, effective and inexpensive, but it has a short retention time under the mucosa, and it is difficult to maintain the height of mucosal uplift for a long time, and submucosal injection is required several times during the operation. Hypertonic saline and glucose can cause local tissue damage, so they are not often used. Sodium hyaluronate is an ideal submucosal injection with high viscosity, which can effectively lift the lesion mucosa and separate it from the mucosal muscle layer

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